Associations between psychological stress, discrimination, and oral health-related quality of life: the buffering effects of social support networks / Associações entre estresse psicológico, discriminação e qualidade de vida relacionada à saúde bucal: os efeitos amortecedores das redes de apoio social / Asociaciones entre estrés psicológico, discriminación y calidad de vida relacionada con la salud bucal: los efectos atenuantes de las redes de apoyo social

Stress and discrimination negatively affect quality of life, but social support may buffer their effects. This study aims: (1) to examine the associations between psychological stress, discrimination, and oral health-related quality of life (OHRQoL); and (2) to assess whether social support, stress and discrimination interact to modify their associations with OHRQoL. We used cross-sectional household-based data from a study including 396 individuals aged 14 years and over from families registered for government social benefits in a city in Southern Brazil. OHRQoL was measured with the Oral Impacts on Daily Performance (OIDP) scale; psychological stress was assessed with the Perceived Stress Scale (PSS); social support was assessed based on the number of close relatives or friends of the participant, and discrimination was assessed with a short version of the Everyday Discrimination Scale. Interactions were estimated using the relative excess of risk due to interaction (RERI). Adjusted effects were calculated with logistic regression. The prevalence of oral impacts among people with higher and lower PSS scores was 81.6% and 65.5%, respectively (p < 0.01). Social support was found to have no interactions with stress levels and discrimination. The association between social discrimination and OHRQoL (OIDP score > 0) was OR = 2.03 (95%CI: 1.23; 3.34) among people with a low level of stress, but was OR = 12.6 (95%CI: 1.31; 120.9) among those with higher levels (p = 0.09, for interaction). Individuals who reported experiencing higher levels of psychological stress and discrimination had worse OHRQoL; a synergistic effect with social support was not clear.

O estresse e a discriminação afetam negativamente a qualidade de vida, mas o apoio social pode amortecer seus efeitos. Os objetivos deste estudo são: (1) examinar as associações entre estresse psicológico, discriminação e qualidade de vida relacionada à saúde bucal (QVRSB); e (2) avaliar se apoio social, estresse e discriminação interagem para modificar suas associações com QVRSB. Os dados são de uma pesquisa transversal de base domiciliar de um estudo que incluiu 396 indivíduos com 14 anos ou mais de famílias registradas para benefícios federais em uma cidade no sul do Brasil. A QVRSB foi mensurada pelo Impactos Orais no Desempenho Diário (OIDP), enquanto o estresse psicológico foi avaliado pela Escala de Estresse Percebido (PSS). Além disso, o apoio social foi avaliado pelo número de parentes ou amigos próximos e a discriminação por meio da Escala de Discriminação Diária (EDS). As interações foram estimadas por meio do excesso relativo de risco devido à interação (RERI). Os efeitos ajustados foram calculados por meio de regressão logística. A prevalência de impactos bucais entre as pessoas com maior e menor escores de PSS foi de 81,6% e 65,5%, respectivamente (p < 0,01). O apoio social mostra interações inclusivas com níveis de estresse e discriminação. A associação entre discriminação social e QVRSB (escore OIDP > 0) foi OR = 2,03 (IC95%: 1,23; 3,34) dentre pessoas com baixo nível de estresse, mas foi de OR = 12,6 (IC95%: 1,31; 120,9) dentre aqueles com níveis mais altos (p = 0,09, para interação). Indivíduos que relataram níveis mais elevados de estresse psicológico e discriminação apresentaram pior QVRSB; o efeito sinérgico com o apoio social não foi evidente.

El estrés y la discriminación afectan negativamente a la calidad de vida, pero el apoyo social puede mitigar sus efectos. Los objetivos de este estudio son: (1) examinar las asociaciones entre el estrés psicológico, la discriminación y la calidad de vida relacionada con la salud bucal (CVRSB); y (2) evaluar si el apoyo social, el estrés y la discriminación interactúan para modificar sus asociaciones con la CVRSB. Los datos provienen de una encuesta transversal de hogares cuyo estudio incluyó a 396 individuos de 14 años o más de familias registradas en beneficios del gobierno en una ciudad del Sur de Brasil. La CVRSB se midió mediante el Impactos Orales en el Rendimiento Diario (OIDP), mientras que el estrés psicológico se evaluó mediante la Escala de Estrés Percibido (PSS). El apoyo social se basó en el número de familiares o amigos cercanos, y la discriminación en la Escala de Discriminación Cotidiana (EDS). Las interacciones se estimaron mediante el excesivo de riesgo relativo debido a la interacción (RERI). Los efectos ajustados se calcularon mediante regresión logística. La prevalencia de impactos orales entre las personas con puntajes de PSS más altas y más bajas fue del 81,6% y del 65,5%, respectivamente (p < 0,01). El apoyo social presenta interacciones inclusivas con niveles de estrés y discriminación. La asociación entre discriminación social y OHRQoL (puntuación OIDP > 0) fue OR = 2,03 (IC95%: 1,23; 3,34) entre personas con un nivel bajo de estrés, pero fue OR = 12,6 (IC95%: 1,31; 120,9) entre aquellos con niveles más altos (p = 0,09, para interacción). Las personas que informaron tener niveles más elevados de estrés psicológico y discriminación tuvieron una peor CVRSB; el efecto sinérgico con el apoyo social no estaba claro.

Health-Related quality of life by 31-item Cervantes scale in breast cancer survivors undergoing adjuvant endocrine therapy

ABSTRACT Introduction Instruments to manage adverse effects of endocrine therapy with Aromatase inhibitors (AI) may improve adherence and persistence to treatment and Health-Related Quality of Life (HRQL). The 31-item Cervantes Scale (CS-31) is an HRQL questionnaire with particularities of the perimenopausal and postmenopausal period that could be an appropriate instrument to assess HRQL in Breast Cancer (BC) survivors. Objective This study aimed to perform additional validation of the CS-31 for BC survivors undergoing adjuvant endocrine therapy. Methods This prospective study was performed at three time points named T0, T1, and T2: initial, intermediate, and final follow-up period, respectively, totaling 24 months of follow-up. At each time point, the participants completed the CS-31, Functional Assessment of Chronic Illness Therapy - Fatigue (FACIT-F), and Hospital Anxiety and Depression Scale (HADS). The internal consistency, construct validity, responsiveness analyses, and known-group validity of CS-31 were evaluated. Results This study included 89 postmenopausal women diagnosed with hormone receptor-positive early BC in adjuvant endocrine therapy with AI. The internal consistency was good (Cronbach's alpha = 0.89). Construct validity received a positive rating, with 100% of results consistent with prior hypotheses. A prospective improvement in HRQL was identified for the CS-31 Global Score and FACIT-F Total Score and for most of their domains. Furthermore, women with anxiety and depression by HADS presented worse HRQL by CS-31. Conclusion The authors identified that the CS-31 seems to be appropriate for use in oncology medical routine and may help to monitor adverse effects and HRQL of BC survivors during adjuvant endocrine therapy.

Influence of genetic polymorphisms on oral health-related quality of life after root canal treatment

Abstract To evaluate the impact of genetic polymorphisms in interleukins (IL1A rs17561, rs1304037; IL10 rs1800871; IL1RN rs9005), nitric oxide (NOS2 rs2779249, rs2897518) and suppressor of cytokine signaling (SOCS1 rs243327, rs33977706) on oral health-related quality of life (OHRQoL) of patients under-going root canal treatment (RCT). Methods: The sample consisted of 108 participants, presenting single-rooted teeth with asymptomatic periapical periodontitis. The impact of the OHRQoL was recorded using the Oral Health Impact Profile (OHIP-14) before, seven, and 30 days after RCT. Saliva samples were collected as a source of genomic DNA. Genetic polymorphisms were genotyped by Real-Time PCR using the Taqman method. Univariate and Multivariate analyses were used (p<0.05). Results: A significant difference was observed for the polymorphism rs2297518 in the NOS2 gene in functional limitation in the codominant (p=0.037) and recessive (p=0.001) models; in the physical pain (p<0.001 in both models); in psychological discomfort (p<0.001 in both models); in physical disability (p<0.001 in both models) and in psychological disability (p<0.001 in both models). Polymorphisms in the SOCS1 gene, in the recessive model, rs33977706 (p=0.045) and rs243327 (p=0.019), influenced the OHRQoL in the psychological discomfort domain. Conclusions: Polymorphisms in NOS2 and SOCS1 genes influenced the OHRQoL of patients undergoing RCT.

Resumo Avaliar o impacto de polimorfismos genéticos em interleucinas (IL1A rs17561, rs1304037; IL10 rs1800871; IL1RN rs9005), óxido nítrico (NOS2 rs2779249, rs2897518) e supressor da sinalização de citocinas (SOCS1 rs243327, rs33977706) na qualidade de vida relacionada à saúde bucal (QVRSB) de pacientes submetidos a tratamento endodôntico (TE). Métodos: A amostra foi composta por 108 participantes, que apresentavam dentes unirradiculares com lesão periapical assintomática. O impacto da QVRSB foi registrado usando o Oral Health Impact Profile (OHIP-14) antes, sete e 30 dias após o TE. Amostras de saliva foram coletadas como fonte de DNA genômico. Os polimorfismos genéticos foram genotipados por PCR em tempo real usando o método Taqman. Análises univariadas e multivariadas foram utilizadas (p<0,05). Resultados: Observou-se diferença significativa para o polimorfismo rs2297518 no gene NOS2 na limitação funcional nos modelos codominante (p=0,037) e recessivo (p=0,001); na dor física (p<0,001 em ambos os modelos); no desconforto psicológico (p<0,001 em ambos os modelos); na deficiência física (p<0,001 em ambos os modelos) e na deficiência psicológica (p<0,001 em ambos os modelos). Polimorfismos no gene SOCS1, no modelo recessivo, rs33977706 (p=0,045) e rs243327 (p=0,019), influenciaram a QVRSB no domínio desconforto psicológico. Conclusões: Polimorfismos nos genes NOS2 e SOCS1 influenciaram a QVRSB de pacientes submetidos a TE.

Clinical efficacy of periodontal endoscopy-assisted subgingival scaling and root planning and its effect on psychology and quality of life in patients with periodontitis / 口腔疾病防治

Objective@#To investigate the clinical efficacy and effects of periodontal endoscope (PE)-assisted subgingival scaling and root planning (SRP) and traditional SRP on the psychological and quality of life of patients with periodontitis.@*Methods@#This study was reviewed and approved by the Ethics Committee, and informed consent was obtained from the patients. Patients with periodontitis who were treated in the Department of Periodontology, Nanjing Stomatological Hospital, Medical School of Nanjing University from April 2018 to December 2022 with residual periodontal pockets (PD ≥ 5 mm) 6 weeks after traditional SRP treatment were enrolled, and the residual periodontal pockets were further treated with PE-assisted SRP (PE+SRP). After 6 weeks of traditional SRP treatment and 3 months of PE+SRP treatment, clinical indicators, including plaque index (PLI), probing depth (PD), clinical attachment loss (CAL) and bleeding on probing (BOP), were measured, and periodontal tissue self-awareness scale scores, oral health impact profile-14 (OHIP-14) score and dental fear scale (DFS) score were collected. Moreover, visual analog scale (VAS) scores were collected after traditional SRP and PE-assisted SRP treatments.@*Results@#Twenty-three patients with periodontitis, including 832 sites of 486 affected teeth, were included in the clinical study. Three months after PE+SRP treatment, all clinical periodontal indicators, PLI (t = 9.254, P<0.001), PD (t = 50.724, P<0.001), CAL (t = 22.407, P<0.001) and BOP (t = 9.217, P<0.001), were significantly improved. Compared with traditional SRP (VAS: 2.48 ± 1.70), the pain caused by PE+SRP (VAS: 2.57±1.80) was not significantly different (t = 0,192, P = 0.850). There was no significant difference in the scores of the periodontal tissue self-awareness scale between the two groups (t = 1.485, P = 0.152). The OHIP-14 (SRP: 12.13±7.63; PE+SRP: 10.26 ± 5.25, t = -1.589, P = 0.126) and DFS (SRP: 40.70 ± 12.63; SRP+PE: 41.57 ± 12.61, t = 0.404, P = 0.690) scores were not significantly different.@*Conclusion@#All clinical periodontal indicators were significantly improved after PE-assisted SRP treatment of residual periodontal pockets, and compared with traditional SRP, PE-assisted SRP had no negative impact on the quality of life or psychological status of patients with periodontitis. Therefore, PE+SRP can be promoted in clinical practice.

Calidad de vida relacionada con la salud en estudiantes de tecnicatura en enfermería / Health-related quality of life among technical nursing students / Qualidade de vida relacionada à saúde em estudantes de técnica de enfermagem

Objetivo: Analizar la calidad de vida relacionada con la salud y sus factores asociados en los estudiantes de la carrera de Tecnicatura en enfermería de una institución de educación superior no universitaria de la Ciudad Autónoma de Buenos Aires, Argentina. Metodología: Estudio descriptivo, transversal y cuantitativo. La muestra estuvo constituida por 204 estudiantes de Tecnicatura en enfermería elegidos mediante muestreo no probabilístico quienes respondieron al instrumento SF-36 durante el primer cuatrimestre del 2023. Resultados: Los encuestados tuvieron una media de edad de 29,87 años (DE: 8,41) y fueron mayormente mujeres (78,92%), solteras (79,41%), sin hijos (59,31%), de segundo año del plan de estudios de la carrera (43,14%) y del turno mañana (40,69%). Relativo al autocuidado, se halló una baja prevalencia de tabaquismo (18,14%) y alta de sedentarismo (67,16%), la mayoría concurren a consulta médica 2 veces al año (58,33%) y se realizan exámenes de sangre anuales (57,35%). Al analizar las dimensiones que componen la calidad de vida relacionada con la salud, se encontró que la Función Física fue la mejor puntuada con una media de 89,95 (DE: 13,45), mientras, Vitalidad obtuvo la valoración más baja con una media de 49,12 (DE: 17,24). Conclusiones: Con excepción de la Vitalidad, todas las dimensiones evaluadas presentaban una valoración positiva. El sexo (hombre), el año del plan de estudios (tercero), el turno (vespertino), el índice de masa corporal (normal) y la implementación de actividades de autocuidado se relacionaron positivamente con la calidad de vida.

Objective: To analyze the quality of life related to health and its associated factors in technical nursing students of a non-university higher education institution in the Autonomous City of Buenos Aires, Argentina. Methods: Descriptive, cross-sectional, and quantitative study. The sample consisted of 204 technical nursing students, selected by non-probabilistic sampling, who responded to the SF-36 instrument during the first quarter of 2023. Results: Respondents had a mean age of 29.87 years (SD: 8.41) and were predominantly female (78.92%), single (79.41%), without children (59.31%), in the second year of the career (43.14%), and working the morning shift (40.69%). Regarding self-care, a low prevalence of smoking (18.14%) and a high prevalence of sedentary lifestyle (67.16%) were found. Most of the students had medical examinations twice a year (58.33%) and had annual blood tests performed (57.35%). When analyzing the dimensions that make up health-related quality of life, it was found that physical function obtained the best evaluation, with a mean of 89.95 (SD: 13.45), while vitality received the lowest evaluation with a mean of 49.12 (SD: 17.24). Conclusions: Except for vitality, all dimensions received a positive evaluation. Gender (male), year of the career (third), shift (evening), Body Mass Index (normal), and self-care activities were positively associated with quality of life.

Objetivo: Analisar a qualidade de vida relacionada com a saúde e seus fatores associados em estudantes de técnica de enfermagem de uma instituição de ensino superior não universitária da Cidade Autónoma de Buenos Aires, Argentina. Metodologia: Estudo descritivo, transversal e quantitativo. A amostra foi composta por 204 estudantes de técnica de enfermagem escolhidos por amostragem não probabilística que responderam ao instrumento SF-36 durante o primeiro quadrimestre de 2023. Resultados: Os entrevistados tinham idade média de 29,87 anos (DP: 8,41) e eram em sua maioria do sexo feminino (78,92%), solteiros (79,41%), sem filhos (59,31%), no segundo ano do curso de enfermagem (43,14%) e no turno da manhã (40,69%). Relativamente ao autocuidado, verificou-se uma baixa prevalência de tabagismo (18,14%) e uma alta prevalência de sedentarismo (67,16%), a maioria foi ao médico duas vezes por ano (58,33%) e fez análises sanguíneas anuais (57,35%). Ao analisar as dimensões que compõem a qualidade de vida relacionada com a saúde, verificou-se que a Função Física foi a mais bem classificada com uma média de 89,95 (DP: 13,45), enquanto a Vitalidade obteve a classificação mais baixa com uma média de 49,12 (DP: 17,24). Conclusões: Com exceção da Vitalidade, todas as dimensões avaliadas foram avaliadas positivamente. O sexo (masculino), o ano curricular (terceiro ano), o turno (noturno), o índice de massa corporal (normal) e a realização de atividades de autocuidado estavam positivamente relacionados com a qualidade de vida.

The association Between Sleep Quality, Fatigue and Periodontal Status: a pilot study / La asociación entre la calidad del sueño, la fatiga y el estado periodontal: un estudio piloto

Abstract Reduced sleep duration, poor sleep quality and fatigue are related to reduced immunity and increased inflammatory markers. Due to its potential to influence inflammation, poor sleep quality and fatigue could be factors for periodontitis and quality of life. Ninety-three individuals with untreated periodontitis and thirty-one individuals with healthy gingiva were included in the study. The research involved a clinical examination and a questionnaire. Demographic information, information on oral health, oral hygiene habits, the Pittsburgh Sleep Quality Index, Jenkins Sleep Scale, Multidimensional Assessment of Fatigue Scale, and Oral Health Impact Profile-14 were included in the questionnaire. Patients were diagnosed based on the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions. No statistically significant difference was revealed between sleep quality, fatigue, oral health related quality of life, and stage-grade of periodontitis (p<0.05). However, periodontitis group had higher Oral Health Impact Profile-14 scores (p<0.05). A statistically significantly lower sleep duration was observed in stage IV periodontitis group than the other groups (p<0.05). A statistically significant positive correlation was observed between the Pittsburgh Sleep Quality Index and the scores of the other questionnaires (p<0.05). The stage of periodontitis may impact sleep duration.

Resumen La reducción de la duración del sueño, la mala calidad del sueño y la fatiga están relacionados con una inmunidad reducida y un aumento de los marcadores inflamatorios. Debido a su potencial para influir en la inflamación, la mala calidad del sueño y la fatiga podrían ser factores determinantes en el desarrollo de la periodontitis e incidir en la calidad de vida. Noventa y tres personas con periodontitis no tratada, además de treinta y una personas con encía sana se incluyeron en el estudio. La investigación involucró un examen clínico y un cuestionario. En el cuestionario se incluyeron información demográfica, información sobre salud bucal, hábitos de higiene bucal, el índice de calidad del sueño de Pittsburgh, la escala de sueño de Jenkins, la escala de evaluación multidimensional de la fatiga y el perfil de impacto en la salud bucal-14. Los pacientes fueron diagnosticados en base al Taller Mundial 2017 sobre la Clasificación de Enfermedades y Condiciones Periodontales y Periimplantarias. No se revelaron diferencias estadísticamente significativas entre la calidad del sueño, la fatiga, la calidad de vida relacionada con la salud bucal y el grado de etapa de la periodontitis (p<0,05). Sin embargo, el grupo de periodontitis tuvo puntajes más altos en el Perfil de Impacto en la Salud Oral-14 (p<0.05). Se observó una duración del sueño significativamente menor desde el punto de vista estadístico en el grupo de periodontitis en estadio IV que en los otros grupos (p<0,05). Se observó una correlación positiva estadísticamente significativa entre el Índice de Calidad del Sueño de Pittsburgh y las puntuaciones de los otros cuestionarios (p<0,05). La etapa de la periodontitis puede afectar la duración del sueño.

Scapular kinesiotaping improves upper extremity functionality in healthy active subjects

SUMMARY OBJECTIVE: The aim of this study was to investigate the effect of scapular kinesiotaping and sham-taping applications on upper extremity functionality in healthy active subjects. METHODS: In total, 60 participants were randomly divided into two groups: scapular kinesiotaping group (n=30) and sham-taping group (n=30). While scapular kinesiotaping was applied to the kinesiotaping group, scapular rigid taping was applied to the sham-taping group. At the end of the third day of the taping application, the individuals were re-evaluated. RESULTS: Participants in the scapular kinesiotaping group showed improvement in upper extremity functionality and quality of life after taping (p<0.05). In the sham-taping group, there was no statistically significant difference after taping (p>0.05). CONCLUSION: Scapular kinesiotaping is effective in improving upper extremity functionality in healthy active subjects.

Calidad de vida relacionada con la salud en niños y niñas con síndrome de Down / Health-related quality of life in children with Down syndrome

Introducción. Los pacientes con síndrome de Down (SD) presentan características que pueden afectar su calidad de vida. El objetivo de este trabajo fue evaluar la calidad de vida relacionada con la salud (CVRS) en pacientes con síndrome de Down. Población y métodos. Se realizó un estudio de corte transversal para evaluar CVRS con el cuestionario PedsQL 4.0 a pacientes de 2 a 4 años con síndrome de Down y a pacientes sanos en 2020-2021 en un hospital universitario. Resultados. Se incluyeron 51 pacientes en cada grupo. El puntaje de CVRS en infantes con SD fue 82,1 vs. 88 (p = 0,003) comparado con población sin SD. La salud psicosocial fue la más afectada (p = 0,007), especialmente, en el funcionamiento social y el escolar (p = 0,0001). Conclusión. Se observó que los niños y niñas con SD de 2 a 4 años tuvieron menor CVRS. La escala de la salud psicosocial fue más afectada, especialmente, el funcionamiento social y el escolar.

Introduction. The characteristics of patients with Down syndrome (DS) may affect their quality of life. The objective of this study was to assess the health-related quality of life (HRQoL) in patients with DS. Population and methods. This was a cross-sectional study to assess the HRQoL with the PedsQL 4.0 questionnaire administered to patients with DS and healthy patients aged 2 to 4 years in 2020­2021 at a teaching hospital. Results. Each study group included 51 patients. The HRQoL score in children with DS was 82.1 compared to 88 (p = 0.003) in the population without DS. Psychosocial health was impacted the most (p = 0.007), especially in terms of social and school functioning (p = 0.0001). Conclusion. Children with DS aged 2 to 4 years were observed to have a lower HRQoL. The psychosocial health scale was affected the most, especially in terms of social and school functioning.

Calidad de vida relacionada con la salud en personas con úlcera venosa / Health-related quality of life of people with venous ulcer / Qualidade de vida relacionada à saúde em pessoas com úlcera venosa

Introducción: la úlcera venosa es la heridade origen vascular que más se presentaen la población adulta; afecta la calidad de vida,por loque se requiereun abordajeinterdisciplinarioparala atenciónde las personas que la padecen. Objetivo:describir las variables clínicas y sociales que interfieren en la calidad de vida relacionada con la salud de un grupo deadultosconúlcera venosa.Métodos:estudio observacional de tipo cohorte; incluyó 80 personas evaluadas en tres clínicas de Medellín(Colombia), en quienes seaplicó elinstrumento de evaluaciónCharing Cross Venous Ulcer Questionnaire. Se describieron las variablessociodemográficas y la evolución de la calidad de vidahasta la cicatrización y se construyó un modelo de regresión logística para explicar las variables asociadas a tener lapeorcalidad de vida. Resultados:el 28,8%de los participantes obtuvieron 64 o más puntos, es decir, grado de afección alto durantela primera mediciónde la calidad de vida;en el 68,8%el puntaje fue63o menos, lo que significó afecciónmoderadaysolo el 2,4%tuvo baja afección.Laspeores puntuaciones se registraron enmujeres,participantes de mayor edad y quienes tenían mayor compromiso de la herida; la afección involucró las dimensiones Estado emocional, Estética, Función social y Actividades domésticas,aunque hubo evolución favorablede la calidad de vidamientrasiba cicatrizandola úlcera. Conclusiones:lacalidad de vida relacionada con la saludestá altamente afectada en las personasque tienen úlcera venosa, siendo más frecuente en quienes tienen dolor constante,heridas más grandes, de mayor tiempo de antigüedad y aquellos con mala percepción desusalud; por tanto,se requiere oportunamentela intervención profesional e interdisciplinaria en salud para el logro de la cicatrizacióny del bienestary para mejorar la calidad de vida.

ntroduction: Venous ulcers are the most common vascular injury in the adult population. They affect the quality of life, so people who suffer from venous ulcers require an interdisciplinary approach to their care. Objective: To describe clinical and social variables that affect the health-related quality of life of a group of adults with venous ulcers. Methods: Observational cohort study carried out with 80 people examined in three medical centers in Medellín (Colombia) and who were given the Charing Cross Venous Ulcer Questionnaire to answer. Sociodemographic variables and the quality-of-life evolution until scarring were described. A logistic regression model was built to explain the variables associated with having the poorest quality of life. Results:There were28.8% of the participants who scored 64 or more points on the first quality of life measurement, which indicates a highly affected quality of life; 68.8% scored 63 or less, indicating a moderately affected quality of life, while only 2.4% indicated a slightly affected quality of life. The worst scores were seen among women, older participants, and those with greater ulcer severity. The dimensions of emotional status, cosmesis, social interaction, and domestic activities were affected, although there was a favorable evolution of the quality of life while the ulcer was healing. Conclusions: Health-related quality of life is highly affected in people with venous ulcers and is more common in those with constant pain, larger and older sores, and those with poor health perceptions. Therefore, timely professional and interdisciplinary healthcare interventions are required to achieve wound healing and wellness and improve quality of life

Introdução:a úlcera venosa é a ferida de origem vascular que ocorre mais frequentemente na população adulta e afeta a qualidade de vida, por isso é necessária uma abordagem interdisciplinar para o cuidado das pessoas que a sofrem. Objetivo:descrever as variáveis clínicas e sociais que interferem na qualidade de vida relacionada à saúde de um grupo de adultos com úlcera venosa.Métodos:estudo de coorte observacional; incluíram-se 80 pessoas avaliadas em três clínicas em Medellín (Colômbia), nas quais foi aplicado o instrumento de avaliação Charing Cross Venous Ulcer Questionnaire. Descreveram-se as variáveis sociodemográficas e a evolução da qualidade de vida até a cicatrizaçãoe construiu-se um modelo de regressão logística para explicar as variáveis associadas à pior qualidade de vida.Resultados: 28,8% dos participantes obtiveram 64 ou mais pontos, ou seja, alto grau de condição na primeira mensuração da qualidade de vida; em 68,8% a pontuação foi de 63 ou menos, o que significa condição moderada e apenas 2,4% em condição baixa. As piores pontuações foram registradas em mulheres, participantes mais velhos e naqueles com maior complicação da ferida; a afecção,envolvia as dimensões Estado Emocional, Estética, Função Social e Atividades Domésticas, embora houvesse evolução favorável da qualidade de vida enquanto a úlcera cicatrizava. Conclusões:a qualidade de vida relacionada à saúde é altamente afetada em pessoas com úlcera venosa, sendo mais frequente naquelas com dor constante, feridasmaiores, mais antigas e com má percepção de saúde; portanto, é necessária intervenção oportuna profissional e interdisciplinar em saúde para alcançar a cicatrização e o bem-estar e melhorar a qualidade de vida

Interferências da toxicidade financeira na qualidade de vida de adultos com insuficiência renal crônica em tratamento hemodialítico / Interferences of financial toxicity in the quality of life of adults with chronic renal failure undergoing hemodialysis treatment

Resumo: O diagnóstico da doença renal crônica acarreta, muitas vezes, modificações às quais obrigam a pessoa a reduzir a jornada de trabalho, diminuindo a renda familiar, situação que pode ocasionar um fenômeno chamado toxicidade financeira que contribui para redução da qualidade de vida relacionada a saúde. Trata-se de um estudo observacional, analítico e correlacional com corte transversal de abordagem quantitativa, com objetivo de investigar a relação da toxicidade financeira na qualidade de vida relacionada à saúde de pessoas com doença renal crônica em tratamento hemodialítico. A coleta de dados foi realizada de fevereiro de 2022 a maio de 2022 em um grupo de clínicas de diálise de Curitiba-PR e Região Metropolitana. O processo de amostragem foi probabilístico, mas o recrutamento foi por conveniência, obedecendo aos critérios de inclusão: pessoas com doença renal crônica, idade igual ou acima de 18 anos e que estavam em tratamento hemodialítico por período maior que seis meses (n=214). Para realização do estudo, foram utilizados os instrumentos sociodemográfico e clínico, Comprehensive Score For Financial Toxicity - COST e Kidney Disease Quality Of Life - Short Form -KDQOL-SFTM. A análise dos dados foi realizada descritivamente com frequências absolutas e relativas das variáveis da caracterização sociodemográfica e clínica da população do estudo, para os escores da toxicidade financeira e qualidade de vida relacionada à saúde foi usado o odds ratio, modelos de regressão logística bayesiano e o método de análise de variância (Anova). Participaram do estudo 214 pessoas com doença renal crônica, sendo 54,67% do sexo masculino, 52,80% tinham 60 anos ou mais, 53,52% eram casados ou estavam em união consensual, 56,07% tinham de 1 a 3 filhos, mais da metade 54,67% tinham menos de 9 anos de escolaridade, 54,97% eram aposentados, 81,75% apresentavam alguma comorbidade além da doença renal crônica, 59,34% tinham o diagnóstico de doença renal crônica de 1 a 5 anos, 88,26% faziam uso de medicação de uso contínuo, 69,69% não eram tabagistas e 72,89% não ingeriam bebida alcoólica. Em relação à toxicidade financeira, a média do escore total encontrado, considerando todas as unidades de coleta de dados, foi de 20,30/44. Pessoas do sexo feminino e renda familiar mensal de no máximo dois salários-mínimos têm maiores chances de apresentarem algum grau de toxicidade financeira (odds ratio: 0,85; 0,76). Verificou-se que na relação entre as medidas COST e qualidade de vida relacionado à saúde o maior impacto da toxicidade financeira foi associado a pior qualidade de vida relacionado à saúde. Sendo assim, foi identificado neste estudo a existência da toxicidade financeira em pessoas com doença renal crônica em hemodiálise e há, também, associação dos piores graus de toxicidade financeira com características sociodemográficas e clínicas. Portanto, a mensuração da toxicidade financeira pode auxiliar a enfermagem a orientar ações para minimizar esse evento.

Abstract: The diagnosis of chronic kidney disease often entails changes that force the person to reduce the workday, reducing family income, a situation that can cause a phenomenon called financial toxicity that contributes to a reduction in the quality of life related to health. This is an observational, analytical and correlational study with a cross-sectional quantitative approach, with the aim of investigating the relationship between financial toxicity and the health-related quality of life of people with chronic kidney disease undergoing hemodialysis treatment. Data collection was carried out from February 2022 to May 2022 in a group of dialysis clinics in Curitiba-PR and the Metropolitan Region. The sampling process was probabilistic, but the recruitment was for convenience, according to the inclusion criteria: people with chronic kidney disease, aged 18 years or older and who were on hemodialysis for a period longer than six months (n=214). To carry out the study, the sociodemographic and clinical instruments, Comprehensive Score For Financial Toxicity - COST and Kidney Disease Quality Of Life - Short Form -KDQOL-SFTM were used. Data analysis was performed descriptively with absolute and relative frequencies of the variables of the sociodemographic and clinical characterization of the study population, for the scores of financial toxicity and health-related quality of life, the odds ratio, Bayesian logistic regression models and the analysis of variance method (Anova). The study included 214 people with chronic kidney disease, 54.67% male, 52.80% aged 60 years or older, 53.52% married or in a consensual union, 56.07% had 1 to 3 children, more than half 54.67% had less than 9 years of schooling, 54.97% were retired, 81.75% had some comorbidity in addition to chronic kidney disease, 59.34% had a diagnosis of chronic kidney disease from 1 to 5 years, 88.26% used continuous medication, 69.69% were non-smokers and 72.89% did not drink alcohol. Regarding financial toxicity, the mean total score found, considering all data collection units, was 20.30/44. Females with a monthly family income of at most two minimum wages are more likely to have some degree of financial toxicity (odds ratio: 0,85; 0.76). It was found that in the relationship between COST measures and health-related quality of life, the greater impact of financial toxicity was associated with worse health-related quality of life. Therefore, this study identified the existence of financial toxicity in people with chronic kidney disease on hemodialysis and there is also an association of the worst degrees of financial toxicity with sociodemographic and clinical characteristics. Therefore, measuring financial toxicity can help nursing guide actions to minimize this event.

Adherencia al tratamiento como pilar fundamental en la calidad de vida en hemodializados

Introducción: La carga farmacológica en pacientes en hemodiálisis supera a otros pacientes crónicos, la no adherencia al tratamiento presenta implicaciones en la calidad de vida, la supervivencia y el coste económico de su tratamiento. El objetivo fue evaluar el puntaje de calidad de vida relacionada con la salud según el tipo de adherencia al tratamiento en pacientes en terapia de hemodiálisis. Métodos: El estudio es de tipo observacional, prospectivo, transversal y descriptivo, el universo de estudio está compuesto por los pacientes que recibieron hemodiálisis en COSSMIL durante el año 2020, la muestra fue de 27 pacientes, la adherencia al tratamiento se midió a través del Test de Morisky-Green y la calidad de vida relacionada con la salud mediante el Kidney Disease Quality of Life de 36 ítems. Resultados: Se hallaron un total de 7 pacientes adherentes al tratamiento (25,9%). En la escala del 1 al 100, el 100% de las puntuaciones del componente mental y 96,3 % del componente físico fueron menores del puntaje referencial de 50. La subescala de carga de enfermedad renal obtuvo puntuaciones de 0. Conclusión: La calidad de vida de estos pacientes se encuentra notablemente afectada, sin diferencias en relación el tipo de adherencia al tratamiento, donde la subescala de carga de enfermedad renal expresa el mayor impacto sobre la calidad de vida, se identifica la necesidad de fortalecer un abordaje integral clínico médico, multidisciplinario y biopsicosocial que incluya estrategias de afrontamiento y apoyo psicosocial para enfrentar los desafíos socioemocionales asociados a la enfermedad renal crónica.

Introduction: The pharmacological burden in hemodialysis patients exceeds that of other chronic patients, non- adherence to treatment has implications for quality of life, survival and the economic cost of their treatment. The objective was to evaluate the health-related quality of life score according to the type of adherence to treatment in patients on hemodialysis therapy. Methods: The study is observational, prospective, cross-sectional and descriptive, the study universe is made up of patients who received hemodialysis at COSSMIL during 2020, the sample was 27 patients, adherence to treatment was measured by through the Morisky-Green Test and health-related quality of life using the 36-item Kidney Disease Quality of Life. Results: A total of 7 patients adherent to the treatment (25.9%) were found. On the scale from 1 to 100, 100% of the scores for the mental component and 96.3% for the physical component were less than the reference score of 50. The subscale of kidney disease burden obtained scores of 0. Conclusion: The quality of life of these patients is significantly affected, with no differences related to the type of treatment adherence. The subscale of renal disease burden expresses the greatest impact on the quality of life. There is a need to strengthen a comprehensive, multidisciplinary, and biopsychosocial clinical approach that includes coping strategies and psychosocial support to address the socioemotional challenges associated with chronic kidney disease.

Rede neural artificial aplicada na análise da qualidade de vida de adolescentes / Artificial neural network applied in the analysis of health-related quality of life of adolescents / Red neuronal artificial aplicada en el análisis de la calidad de vida relacionada con la salud de los adolescentes

Objetivo: construir um modelo que explique a qualidade de vida relacionada à saúde entre adolescentes escolares a partir do instrumento KIDSCREEN-27 por meio da criação de uma rede neural artificial. Método: estudo transversal e analítico com 635 adolescentes utilizando-se o KIDSCREEN-27. Foi desenvolvida uma rede neural artificial com quatro camadas para avaliar a variável qualidade de vida relacionada à saúde por meio da média das respostas. Para as três primeiras camadas de neurônios foi utilizada função logística como função de transferência e para a ativação foi utilizada função linear. Resultados: a rede neural alcançou acurácia de 98,96% e quando comparadas as dimensões do KIDSCREEN-27 com sexo e prática de atividades físicas todas apresentaram associação estatística significativa, exceto as dimensões suporte social e grupo de pares e ambiente escolar. Conclusão: os resultados podem ter importantes consequências para a identificação de adolescentes em risco e o direcionamento de políticas públicas de saúde

Objective: to construct a model that explains the health-related quality of life among school adolescents from the KIDSCREEN-27 instrument through the creation of an artificial neural network. Method: cross-sectional and analytical study with 635 adolescents using KIDSCREEN-27. An artificial neural network with four layers was developed to evaluate the variable health-related quality of life by means of the mean responses. For the first three layers of neurons, logistic function was used as transfer function and linear function was used for activation. Results: the neural network reached accuracy of 98.96% and when compared the dimensions of kidscreen-27 with sex and practice of physical activities all presented significant statistical association, except the dimensions social support and peer group and school environment. Conclusion: the results may have important consequences for the identification of adolescents at risk and the direction of public health policies

Objetivo: construir un modelo que explique la calidad de vida relacionada con la salud de los adolescentes escolares a partir del instrumento KIDSCREEN-27 a través de la creación de una red neuronal artificial. Método: estudio transversal y analítico con 635 adolescentes utilizando KIDSCREEN-27. Se desarrolló una red neuronal artificial con cuatro capas para evaluar la variable calidad de vida relacionada con la salud mediante las respuestas medias. Para las tres primeras capas de neuronas, la función logística se utilizó como función de transferencia y la función lineal se utilizó para la activación. Resultados: la red neuronal alcanzó una precisión del 98,96% y cuando se compararon las dimensiones de kidscreen-27 con el sexo y la práctica de actividades físicas todos presentaron una asociación estadística significativa, excepto las dimensiones de apoyo social y grupo de pares y entorno escolar. Conclusión:los resultados pueden tener consecuencias importantes para la identificación de adolescentes en riesgo y la orientación de las políticas de salud pública

Cárie na primeira infância, má oclusão, fatores psicossociais e qualidade de vida relacionada à saúde bucal de crianças e suas famílias / Early childhood caries, malocclusion, psychosocial factors and oral health-related quality of life in children and their families

Cárie na primeira infância (CPI) e má oclusão podem afetar a qualidade de vida relacionada à saúde bucal (QVRSB) de crianças e suas famílias. Fatores psicossociais relacionados às crianças, suas famílias e comunidade na qual estão inseridas devem ser estudados. Diante disso, os objetivos desta tese foram: 1) verificar a associação entre fatores psicossociais associados à CPI e à QVRSB em pré-escolares e suas famílias (Artigo 1); 2) avaliar o impacto da mordida aberta anterior (MAA) e da mordida profunda (MP) na QVRSB de préescolares, e verificar o papel da resiliência parental como um fator moderador nessa associação (Artigo 2). Foi realizado um estudo transversal representativo com pré-escolares de 4-6 anos de idade e seus pais/responsáveis em Ribeirão das Neves, MG, Brasil. Os pais/responsáveis responderam às versões brasileiras do Early Childhood Oral Health Impact Scale (ECOHIS) e Escala de Resiliência, e um questionário com dados socioeconômicos e de comportamento de saúde bucal da criança. Os pré-escolares foram examinados por duas dentistas treinadas e calibradas para o diagnóstico de CPI e consequências pulpares de lesões cariosas não tratadas (Kappa>0,95), utilizando-se a versão epidemiológica do International Caries Detection and Assessment System (ICDASepi) combinado com o índice pufa e, assim categorizados: sem cárie, estágio inicial (opacidade notável/pigmentação retida em fundo de fóssulas e fissuras), estágio moderado (cavitação em esmalte/sombreamento em dentina subjacente), estágio extenso sem consequências pulpares (cavitação com exposição dentinária) e estágio extenso com consequências pulpares (cavitação com exposição dentinária, com envolvimento pulpar e/ou presença de fístulas/abscessos). A presença de MAA e MP foi avaliada através do índice de Foster e Hamilton. Os dados foram analisados por meio da modelagem por equações estruturais, utilizando-se o software Mplus, versão 8.6 (Artigo 1) e por meio da análise de moderação, utilizando-se o PROCESS (PROCESS for SPSS, version 3.4) (Artigo 2). Os resultados do artigo 1 demonstraram que menor status socioeconômico (ß =-0,250; p<0,001) e maior frequência de consumo de açúcares livres (ß=0,122; p=0,033) foram associados diretamente com estágio extenso de cárie com consequência pulpar, enquanto menor resiliência dos pais impactou indiretamente estágios mais avançados da CPI, por meio da variável frequência de consumo de açúcares livres (ß =-0,089; p=0,048). Além disso, CPI foi associada com piores escores tanto da QVRSB da criança (b=0,587; p<0,001) quanto da família (ß =0,506; p<0,001). Os resultados do artigo 2 demonstraram que préescolares filhos de pais com baixa resiliência, e que possuíam MAA apresentaram impacto negativo na QVRSB (ß:3,95;p=0,025) em comparação àqueles que apresentaram oclusão normal. A resiliência parental não atuou como fator moderador na associação entre MP e QVRSB (p>0,05). Conclui-se que quanto maior a gravidade da CPI, maior o impacto negativo na QVRSB de pré-escolares e suas famílias. Os principais fatores associados à CPI mais grave foram menor nível socioeconômico, maior frequência de consumo de açúcar livre e menor resiliência parental (Artigo 1). MAA interferiu negativamente na QVRSB dos pré-escolares, sendo essa associação mais forte quando a resiliência parental era baixa. Portanto, a resiliência dos pais atuou como fator moderador na relação entre MAA e QVRSB (Artigo 2).

Early childhood caries (ECC) and malocclusion can affect the oral health-related quality of life (OHRQoL) of children and families. Psychosocial factors related to children, their families and the community in which they are inserted must be studied. Therefore, the objectives of this thesis were: 1) to verify the association between psychosocial factors with ECC and OHRQoL in preschoolers and their families (Manuscript #1); 2) to evaluate the impact of anterior open bite (AOB) and deep bite (DB) on the OHRQoL of preschool children and the role of parental resilience as a moderating factor in such association (Manuscript #2). A representative crosssectional study was carried out with 4-to-6-year-old preschoolers and their parents/caregivers from Ribeirão das Neves, MG, Brazil. Parents/caregivers selfadministered the Brazilian versions of the Early Childhood Oral Health Impact Scale (ECOHIS) and the Resilience Scale, as well as a questionnaire about socioeconomic and child's oral health behavior data. Preschoolers were examined by two trained and calibrated dentists for the diagnosis of ECC and pulpal consequences of untreated carious lesions (Kappa>0.95), using the epidemiological version of the International Caries Detection and Assessment System (ICDASepi) index combined with the pufa index: no caries, early stage (notable opacity/retained pigmentation in the background of pits and fissures), moderate stage (cavitation in enamel/shading in underlying dentin), extensive stage without pulpal consequences (cavitation with dentin exposure) and extensive stage with pulpal consequences (cavitation with dentin exposure, and pulp involvement and/or fistulas/abscesses). The presence of AOB and DB were evaluated using the Foster and Hamilton index. Data were analysed through Structural Equation Model (SEM), using the Mplus software, version 8.6 (Manuscript #1) and through moderation analysis, using PROCESS (PROCESS for SPSS, version 3.4) (Manuscript #2). The results of the Manuscript #1 demonstrated that lower socioeconomic status (b=-0.250; p<0.001) and higher frequency of consumption of free sugars (ß=0.122; p=0.033) were directly associated with an extensive stage of caries with pulpal consequences, while lower parental resilience indirectly impacted more advanced stages of ECC, through the variable frequency of consumption of free sugars (b=-0.089; p=0.048). In addition, ECC was associated with worse scores in both the child's (ß=0.587; p<0.001) and the family's (ß=0.506; p<0.001) OHRQoL. The results of the Manuscript #2 demonstrated that preschoolers whose parents presented low resilience, and preschoolers who presented OAB, had a negative impact on OHRQoL (ß:3.95; p=0.025) compared to those who had normal occlusion. Parental resilience did not act as a moderating factor in the association between DB and OHRQoL (p>0.005). It is concluded that the severity of ECC negatively impacted the OHRQoL of preschoolers and their families, and the main factors associated with the severity of ECC were lower socioeconomic status, higher frequency of free sugar consumption and lower parental resilience (Manuscript #1). OAB negatively interfered with the OHRQoL of preschoolers, with this association being stronger when parental resilience was low. Therefore, parental resilience acted as a moderating factor in the relationship between OAB and OHRQoL (Manuscript # 2).

Nivel de actividad física y calidad de vida relacionada con la salud en estudiantes universitarios / Physical Activity Level and Health-Related Quality of Life in University Students

Introducción. La etapa universitaria trae consigo una serie de experiencias y retos nuevos, por lo que existen diferentes factores que alteran los niveles generales de actividad física y de la calidad de vida relacionada con la salud. Esta investigación buscó establecer la relación entre el nivel de actividad física y la calidad de vida relacionada con la salud en los estudiantes pertenecientes a la facultad de educación de una universidad privada de la ciudad de Medellín. Método. Se llevó a cabo un estudio cuantitativo con un alcance correlacional con un total de 252 estudiantes pertenecientes a la facultad de educación de una universidad de Medellín, seleccionados de forma aleatoria a partir de un muestreo probabilístico estratificado; se aplicó el Cuestionario Internacional de Actividad Física (IPAQ-SF) y el de Calidad de Vida Relacionada con la salud (SF-36).Resultados. Se encontró que la mayoría de los estudiantes (60,3%) tienen un nivel moderado de actividad física y que, a mejor nivel de actividad física, mejor es la percepción frente a la evolución declarada de la salud. No se hallaron asociaciones significativas entre el nivel de actividad física y las dimensiones de la calidad de vida relacionada con la salud. Conclusiones. El nivel de actividad física tiende a ser independiente de las dimensiones de la calidad de vida relacionada con la salud

Introduction. The university stage brings with it a series of new experiences and challenges, so there are different factors that alter the general levels of physical activity and the health-related quality of life. This research sought to establish the relationship between the level of physical activity and the health-related quality of life in students belonging to the faculty of education of a private university in the city of Medellín.Method. A quantitative study with a correlational scope was carried out, with a total of 252 students belonging to the faculty of education of a university in Medellin, which were selected randomly from a stratified probabilistic sampling; the International Physical Activity Questionnaire (IPAQ-SF) and the of Health-Related Quality of Life (SF-36) were applied.Results. It was found that most of the students (60.3%) have a moderate level of physical activity and that, the better the level of physical activity, the better the perception of the declared evolution of health. No significant associations were found between the level of physical activity and the dimensions of the quality of life related to health.Conclusions. The level of physical activity tends to be independent of the dimen-sions of health-related quality of life

Condições de vida de pessoas vivendo com HIV em um município do Estado do Rio de Janeiro, Brasil / Life conditions of people living with HIV in a city of the state of Rio de Janeiro, Brazil / Condiciones de vida de las personas que viven con el VIH en un municipio del estado de Río de Janeiro, Brasil

Objetivo: discorrer sobre as condições de vida das pessoas vivendo com HIV em um município do estado do Rio de Janeiro, Brasil. Método: estudo do tipo transversal, descritivo, de natureza qualitativa. A coleta de dados foi através de entrevistas, sendo os achados submetidos à técnica de análise de conteúdo. A amostra foi composta por pessoas vivendo com HIV que eram abordados no momento que compareciam ao serviço de assistência especializada, sendo definida uma amostra de 20 participantes por técnica de saturação. Resultado: emergiram categorias com base nos temas abordados na entrevista relacionados à qualidade de vida (condição de alimentação, atividade física, lazer, religião e satisfação com a vida sexual) e à experiência de viver com HIV. Conclusão: as pessoas vivendo com HIV, em tratamento antirretroviral, podem usufruir de boas condições de vida tendo como principal fator impeditivo o medo de vivenciar situações de estigma e discriminação.

Objectives: investigate the implications for the life conditions of people living with HIV in a city of the State of Rio de Janeiro, Brazil. Method: cross-sectional, descriptive, and qualitative study. Data collection was conducted through interviews, and the findings were subjected to the content analysis technique. The sample comprised people living with HIV that were approached at the time they attended the specialized assistance service, and a sample of 20 participants was defined by saturation technique. Result: categories emerged based on the topics addressed in the interview related to quality of life (food condition, physical activity, leisure, religion, and satisfaction with sexual life) and the experience of living with HIV. Conclusion: people living with HIV in antiretroviral treatment can enjoy good living and the preventing potential factor is the fear of experiencing situations of stigma and discrimination.

Objetivos: conocer las implicaciones para las condiciones de vida de las personas que viven con el VIH en un municipio del Estado de Río de Janeiro, Brasil. Método: estudio de tipo transversal, descriptivo, de naturaleza cualitativa. La recolección de datos se realizó a través de entrevistas, y los hallazgos fueron sometidos a la técnica de análisis de contenido. La muestra se compuso por personas que viven con el VIH que fueron abordadas en el momento en que vinieron al servicio de asistencia especializada, y se definió una muestra de 20 participantes por la técnica de saturación. Resultado: emergieron categorías basadas en los temas abordados en la entrevista relacionados con la calidad de vida (condición alimentaria, actividad física, ocio, religión, y satisfacción con la vida sexual) y la experiencia de vivir con VIH. Conclusión: las personas que viven con el VIH en tratamiento antirretroviral pueden disfrutar de buenas condiciones de vida y salud, y el principal impedimento y el temor de experimentar situaciones de estigma y discriminación.

Medication adherence and health-related quality of life amongst HIV patients receiving care at umuebule cottage hospital, etched, Rivers State

HIV treatment is available, free, and accessible for individuals who are infected. The study is aimed at determining the levels of medication adherence and health related quality of life (HRQOL) among HIV patients receiving care at Umuebule Cottage Hospital, Etche, Rivers State.Method: This cross-sectional study recruited 430 adult clients who have been on ART for at least one year using a convenient sampling method. An average of 10 patients visits the facility on clinic days. After explaining the purpose of study and obtaining consent,patients who met the eligibility criteria were recruited on each clinic day for a period of 12 weeks, until the sample size was reached. Data was collected using semi-structured interviewer administered validated questionnaire; Morisky Medication Adherence Questionnaire (MMAS-8) and WHO-Quality of Life-BREF(WHOQOL-BREF), after a pilot study on 30 PLHIV from Okomoko general hospital, Etche. Data was analyzed with IBM-SPSS Version 25. The mean age of respondents was 35.9±10.9 years, 59.3% of the respondents' last viral load was suppressed, 19.1% had low level viremia, while (21.6%) were virally unsuppressed. Medication adherence levels were observed to be good (67.7%), poor (32.3%) respectively, while HRQOL of respondents were found to be poor (56.9%) and good (43.1%).Conclusion:A significant proportion of the respondents adhere to their medication whereas most of them had poor HRQOL. There is need for hospital management to collaborate with social welfare organizations to support PLHIV to set up means of earning to enable them to provide their basic needs for improved HRQOL

The impact of health related quality of life for children and adolescents aged 8-15 years in Nanjing / 中国学校卫生

Objective@#To investigate the impact of COVID-19 infection and health related behaviors on the health related quality of life of children and adolescents aged 8-15 years in Nanjing, so as to provide a theoretical basis for improving HRQoL in children and adolescents.@*Methods@#From December 2022 to January 2023, a total of 2 398 students aged 8-15 years from the third grade of primary school to junior middle school in Nanjing were selected by multistage random cluster sampling. The 3 level EuroQol 5 dimension Questionnaire Youth Vension (EQ-5D-Y-3L) was completed by the respondents on their own, and the parents assisted in completing the rest of the questionnaire.@*Results@#The EuroQol-index(EQ-index) and Visual Analogue Scale (VAS) scores of being infected individuals were lower than those of uninfected and previously infected ( P <0.05). The proportion of being infected individuals reporting difficulty on "Pain/Discomfort" was higher than that of uninfected and previously infected individuals, and the proportion of reporting difficulty on "Mobility" was also higher than that of uninfected individuals ( P <0.05). Lack of parental companionship( OR=10.19, 95%CI =3.12-33.22), irregular breakfast consumption ( OR=10.63, 95%CI =3.20-35.25), and excessive screen time ( OR=8.24, 95%CI =3.02-22.51) increased the risk of difficulty on "Mobility" in being infected individuals ( P <0.05). Irregular breakfast consumption ( OR=1.93, 95%CI =1.31-2.84) and consumption of sweetened beverages and snacks (OR=1.56, 95%CI =1.17-2.10) increased the risk of having lower EQ index in previously infected individuals compared to uninfected individuals. Furthermore, consumption of sweetened beverages and snacks ( OR=1.57, 95%CI =1.21-2.05) and excessive screen time ( OR=1.49, 95%CI =1.12-1.98) also increased the risk of VAS scores being lower in previously infected individuals compared to uninfected individuals ( P <0.05).@*Conclusion@#The COVID-19 infection impairs HRQoL, and unhealthy behaviors deteriorate its negative impact. Healthy behaviors and lifestyles should be advocated to reduce the impact of COVID-19 infection on HRQoL.

Association between oral health behavior during pregnancy and premature birth based on case-control study / 西安交通大学学报(医学版)

【Objective】 To investigate the relationship between maternal oral health behavior during pregnancy and premature birth. 【Methods】 A total of 248 preterm and 700 non-preterm pregnant women who delivered in Northwest Women’s and Children’s Hospital in Shaanxi Province from January to December 2022 were included in case group and control group, respectively. General demographic characteristics and oral health behavior during pregnancy were collected by questionnaires, and the oral health impact profile-14 (OHIP-14) was used to assess the oral health related life quality of pregnant women. Logistic regression model was used to analyze the relationship between maternal oral health behavior during pregnancy and premature birth. 【Results】 During pregnancy, maternal frequent eating after brushing teeth (OR=1.62, 95% CI: 1.03-2.57), unused fluoride toothpaste (OR=2.03, 95%CI: 1.25-3.05), late visit to the doctor for oral discomfort (OR=1.41, 95%CI: 1.02-1.96), brushing teeth less than twice one day (OR=1.77, 95%CI: 1.13-2.78) or less than 3 minutes each time (OR=1.52, 95%CI: 1.09-2.11), and elevated OHIP-14 score (OR=1.07, 95%CI: 1.04-1.10) increased the risk of premature birth. 【Conclusion】 Poor oral health behavior during pregnancy may increase the risk of premature birth. Therefore, more efforts should be made to publicize oral health knowledge and guide pregnant women to establish good oral health habits so as to improve oral health and promote maternal and child health.

Nutrient intake, oral symptoms, and oral health-related quality of life among antenatal mothers in Sarawak

@#Introduction: This study aimed to determine the association between nutrient intake, oral symptoms, and oral health-related quality of life (OHRQoL) among antenatal mothers in the Sri Aman district, Sarawak. Methods: A total of 124 antenatal mothers in the second and third trimesters, through systematic random sampling, participated in this cross-sectional study. A validated selfadministered questionnaire was used to collect their socioeconomic and obstetric profiles, perceived oral health status, and OHRQoL. Three days 24-hour diet recall assessment involving two weekdays and one weekend day was used for nutrient intake assessment. Results: Most mothers (75.0%) had at least one oral symptom: cavitated tooth (51.6%), bleeding gum (32.3%), halitosis (27.4%), gum pain (13.7%), toothache (12.1%), and swollen gum (6.5%). Most mothers also had inadequate intakes of energy, vitamin D, iodine, calcium, zinc, fluoride, and iron. The most affected OHRQoL domain was psychological discomfort, followed by functional limitation and physical pain. Nutrient intake was not significantly different between antenatal mothers with and without oral symptoms. Antenatal mothers with at least one oral symptom, presence of toothache, cavitated tooth, bleeding gum, and halitosis had significantly lower OHRQoL. Conclusion: Most antenatal mothers had inadequate nutrient intake, particularly vitamin D and calcium. Nutrient intake was not significantly associated with oral symptoms. The oral symptoms of dental caries and periodontal disease were prevalent; and the presence of toothache, cavitated tooth, bleeding gum, and halitosis were associated with poor OHRQoL.

Content comparison of assessment tools of activity and participation, and quality of life: based on ICD-11 and ICF / 中国康复理论与实践

ObjectiveTo encode and analyze the measurement items of major activity and participation function assessment tools and quality of life assessment tools using International Classification of Functioning, Disability and Health (ICF). MethodsRepresentative tools in the activity category, comprehensive activity and participation category, as well as quality of life assessment tools were selected for analysis of their measurement structures and content. Based on the ICF linking rule and content matching method, the concepts of measurement items in various tools were matched with ICF categories, analyzing the relationships between the content of measurement items and the concepts of ICF categories, and then coded in ICF and ICD-11. ResultsMeasurement tools in the activity category, such as Barthel index (BI) and Instrumental Activities of Daily Living (IADL), were primarily standardized activity assessment tools in medical, rehabilitation, and community settings. The measurement was conducted through direct observation of activity function and semi-structured interviews with individuals or their caregivers, with 25 to 60 minutes. Most measurement tools were standardized reference tools. Assessment tools related to overall functioning in the activity and participation category, such as 36-item Short-Form Health Survey (SF-36), World Health Organization Quality of Life Questionnaire (WHOQOL-BREF), World Health Organization Quality of Life-Disability (WHOQOL-DIS) and World Health Orgnization Disability Assessment Scheme 2.0 (WHODAS 2.0) were norm-referenced assessment tools applicable in medical, rehabilitation, education, and social service contexts. The measurement was carried out by professionals through interviews and observations, or completed by the assessed individuals through self-administered questionnaires, with a measurement duration of 30 to 60 minutes. In terms of measurement content, IADL and BI mainly focus on activities of self care and functional activities, corresponding to ICF categories such as mobility (d4), self-care (d5), and domestic life (d6). SF-36 primarily covers general tasks and demands (d2), communication (d3), mobility (d4), self-care (d5), and domestic life (d6). WHOQOL-BREF and WHOQOL-DIS items related to general tasks and demands (d2), communication (d3), mobility (d4), interpersonal interactions and relationships (d7), and community, social, and civic life (d9). WHODAS 2.0 was the most comprehensive measurement tool covering all nine domains of activity and participation in the ICF. ConclusionThis study amalyzed the structures and contents of items of six assessments tools using ICF nomenclature, terminology, codes and linking rules. WHOQOL-BREF, WHOQOL-DIS and WHODAS 2.0 are comprehensive functioning evaluation tools, covering all nine ICF domains of activity and participation, as well as quality of life and well-being.